Hippocampus and cerebellum damage in sepsis induced by lipopolysaccharide in aged rats - Pregabalin can prevent damage

ASLANKOÇ, Rahime; SAVRAN, Mehtap; Ozmen, Ozlem; AŞCI, Sanem

doi:10.1016/j.biopha.2018.09.162

Hippocampus and cerebellum damage in sepsis induced by lipopolysaccharide in aged rats - Pregabalin can prevent damage

ASLANKOÇ R., SAVRAN M., Ozmen O., AŞCI S.

BIOMEDICINE & PHARMACOTHERAPY, vol.108, pp.1384-1392, 2018 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 108
Publication Date: 2018
Doi Number: 10.1016/j.biopha.2018.09.162
Journal Name: BIOMEDICINE & PHARMACOTHERAPY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1384-1392
Süleyman Demirel University Affiliated: Yes

Abstract

Backgrounds: The aim of this study was to investigate the oxidative damage and inflammatory effects in the hippocampus and cerebellum in lipopolysaccharide (LPS)-induced sepsis model and possible ameliorating effects of pregabalin (PG).