JOURNAL OF PERIODONTOLOGY, vol.87, no.11, 2016 (Peer-Reviewed Journal)
Article / Article
JOURNAL OF PERIODONTOLOGY
Science Citation Index Expanded, Scopus
Alveolar bone loss, curcumin, interleukin-17, interleukin-23, periodontitis, Th17, TH17 CELLS, ANTIINFLAMMATORY AGENT, IL-17, AUTOIMMUNE, DISEASE, LIGAND, SITES, BETA, DIFFERENTIATION, PROGRESSION
Background: Curcumin has anti-inflammatory and antioxidant effects and is reported to have many biologic activities. The current study examines effect of curcumin on: 1) systemic T helper 17 (Th17) cell response; 2) gingival expressions of interleukin (IL)-17 and retinoic acid receptor-related orphan receptor (ROR) gamma t; and 3) alveolar bone loss (ABL) in experimental periodontitis.