Evaluation of biochemical, hematological, RIBA and PCR assays in predicting viremia in anti-HCV positive patients


ŞİRİN M. C. , Aridogan B. C. , Cetin E. S. , ŞİRİN F. B.

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, vol.13, no.8, pp.736-743, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 8
  • Publication Date: 2019
  • Doi Number: 10.3855/jidc.11426
  • Title of Journal : JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
  • Page Numbers: pp.736-743
  • Keywords: antibody titer, hepatitis C, polymerase chain reaction, viremia, MEAN PLATELET VOLUME, TO-CUTOFF RATIOS, HEPATITIS-C, INFECTION, DIAGNOSIS, MARKER, S/CO, RNA

Abstract

Introduction: The detection of HCV-RNA by PCR assays is considered to be the gold standard for confirming the presence of HCV viremia. However, high costs, long and laborious procedures limit their widespread usage. This retrospective study was conducted to assess the predictive performances of biochemical and hematological parameters, anti-HCV signal-to-cutoff (S/CO) ratios and RIBA assay for HCV viremia.